学历：
泉州师范学院理学学士，生物学专业
厦门大学理学博士，动物学专业
研究方向：
利用电磁脉冲进行肿瘤治疗的技术开发，优化与分子机制研究
主讲课程：
电磁场与微波技术实验课（本科生课）
课题项目：
1.深圳市科技计划项目，JCYJ20180306173301083，利用细胞模型及计算机预测方法探究二甲苯麝香致癌的分子机制，2019/01-2021/12,30万元，在研，主持。
2.国家自然科学基金青年科学基金项目，21407120，人工麝香诱导肝细胞恶性转化及其分子机制的研究，2015/01-2017/12，26万元，结题，主持。
3.福建省公益类项目，2015R1101031-4，二甲苯麝香诱导肝细胞恶性转化及其分子机制的研究，2015/10-2017/9，6万元，结题，主持。
代表作：
(1) Zheng Mao, Youyu Zhang,* Nan Lu, Shun Cheng, Ronghan Hong, and Qing Huo Liu*.2020. Carbon Nanotubes Enabling Highly Efficient Cell Apoptosis by Low-Intensity Nanosecond Electric Pulses via Perturbing Calcium Handling.Small.16:1904047.
(2) Zhang, Y., Mao, Z., Wang, B., Zhang, J., Lu, N., Hong, R., ... & Liu, Q. H*. 2019. Enhanced antitumor efficacy achieved through combination of nsPEFs and low-dosage paclitaxel. IEEE Transactions on Biomedical Engineering.66(11):3129-3135.
(3) Huang, L., Zhang, Y., He, R., Zuo, Z., Luo, Z., Xu, W., & Yan, Q. 2019. Phenotypic characterization, virulence, and immunogenicity of Pseudomonas plecoglossicida rpoE knock-down strain. Fish & shellfish immunology, 87, 772-777.
(4) Zhang, Y.Y., Huang, L. X., Zhao, Y, J., Hu, T, H. 2017. Musk xylene induces malignant transformation of human liver cell line L02 via repressing the TGF- β signaling pathway. Chemosphere 168: 1506-1514.
(5) Dandan Li1, Youyu Zhang1,3,… Tianhui Hu1 .Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth.2017. Laboratory Investigation.1-11.
(6) Huang,L., Xi,Z., Wang,C., Zhang,Y., Yang,Z., Zhang,S., Chen,Y., Zuo,Z.2016. Phenanthrene exposure induces cardiac hypertrophy via reducing miR-133a expression by DNA methylation. Sci Rep. 6: 2010-5.
(7) Hong, Z., Zhang, Y. Y., Zuo, Z. H., Zhu, R. L., Gao, Y. H. 2015. Influences of Domoic Acid Exposure on Cardiac Development and the Expression of Cardiovascular Relative Genes in Zebrafish (Daniorerio) Embryos. J Biochem Mol Toxicol. 29(6), 254-60.
(8) Huang, L. X., Gao, D. X., Zhang, Y. Y., Wang, C. G., Zuo, Z. H. 2014. Exposure to low dose benzo[a]pyrene during early life stages causes symptoms similar to cardiac hypertrophy in adult zebrafish. J Hazard Mater. 276: 377-82.
(9) Huang, L. X., Zuo, Z. H., Zhang, Y. Y., Wang, C. G. 2014. Toxicogenomic analysis in the combined effect of tributyltin and benzo[a]pyrene on the development of zebrafish embryos. Aquat Toxicol. 158C: 157-164.
(10) Huang, L. X., Zuo, Z. H., Zhang, Y. Y., Wu, M. F., Lin, J. J., Wang, C. G. 2014. Use of toxicogenomics to predict the potential toxic effect of Benzo(a)pyrene on zebrafish embryos: ocular developmental toxicity. Chemosphere. 108:55-61.
(11) Zhang, Y. Y., Huang, L. X., Zuo, Z. H., Chen, Y. X., Wang, C. G. 2013. Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling. Aquat Toxicol. 142-143:26-32.
(12) Zhang, Y. Y., Huang, L. X., Wang, C. G., Gao, D. X., Zuo, Z. H. 2013. Phenanthrene exposure produces cardiac defects during embryo development of zebrafish (Danio rerio) through activation of MMP-9. Chemosphere. 93(6):1168-75.
(13) Huang, L. X., Wang, C. G., Zhang, Y. Y., Wu, M. F., Zuo, Z. H. 2013. Phenanthrene causes ocular developmental toxicity in zebrafish embryos and the possible mechanisms involved. J Hazard Mater. 261: 172-80.
(14) Zhang, Y. Y., Wang, C. G., Huang, L. X., Chen, R., Chen, Y. X., and Zuo, Z. H. 2012. Low-level pyrene exposure causes cardiac toxicity in zebrafish (Danio rerio) embryos. Aquat. Toxicol. 114-115: 119-124.
(15) Huang, L. X., Wang, C. G., Zhang, Y. Y., Li, J., Zhong, Y. F., Zhou, Y. L., Chen, Y. X., and Zuo, Z. H. 2012. Benzo[a]pyrene exposure influences the cardiac development and the expression of cardiovascular relative genes in zebrafish (Danio rerio) embryos. Chemosphere. 87(4), 369-75.
